Entry 1 sense Webster, 1913 Craniofacial /(-f?"shal)/ · Cra·ni·o·fa·cial · IPA /kɹeɪ.nɪ.əˈfeɪ.ʃəl/ 01 a. Of or pertaining to the cranium and face; as, the craniofacial angle. 1. Of or pertaining to the cranium and face; as, the craniofacial angle.