Entry 1 sense Webster, 1913 Cupellation /(kū`pĕl*lā"shŭn)/ · Cu·pel·la·tion · IPA /kjuːpəˈleɪʃən/ 01 n. The act or process of refining gold or silver, etc., in a cupel. 1. The act or process of refining gold or silver, etc., in a cupel.