Malignance /(?)/

Ma·lig·nance

Malignance

n.
  1. The state or quality of being malignant; extreme malevolence; bitter enmity; malice; disposition toward evil; intense ill will; as, malignancy of heart.
  2. Unfavorableness; evil nature.
    The malignancy of my fate might perhaps distemner yours.
  3. Virulence; tendency to a fatal issue; as, the malignancy of an ulcer or of a fever. (Med.)
  4. A cancerous tumor that is spreading beyond the point of origin. (Med.)
  5. The state of being a malignant.