Entry 1 sense Webster, 1913 Moon shot /(mo͞on" shŏt)/ · Moon· shot · IPA /ˈmuːn ʃɑt/ 01 n. The action or event of sending a spacecraft to the moon; -- used of manned or unmanned missions. 1. The action or event of sending a spacecraft to the moon; -- used of manned or unmanned missions.