Vicissitude /(?)/

Vi·cis·si·tude

Vicissitude

n.
  1. Regular change or succession from one thing to another; alternation; mutual succession; interchange.
    God made two great lights . . . To illuminate the earth and rule the day In their vicissitude, and rule the night.
  2. Irregular change; revolution; mutation.
  3. Changing conditions of fortune in one's life; life's ups and downs.
    This man had, after many vicissitudes of fortune, sunk at last into abject and hopeless poverty.